Medications Which Cause Depression

Depression is a condition which is characterized by persistently feeling sad, hopeless and helpless. These feelings can be compounded by difficulties concentrating or making relatively simple decisions and losing interest in everyday activities.

Excessive sleepiness and weight gain due to overeating are other symptoms of depression though some patients develop insomnia and lose weight as their appetite dwindles. 

Headaches, indigestion and body aches that do not improve with treatment are also typical of depression.

Suicidal ideation or thinking about committing suicide is another serious symptom of depression which must be addressed quickly.

Depression Causing Prescription Medications

Medications which can cause depression include:
1. Beta blockers like atenolol, metoprolol and carvedilol which are used to treat high blood pressure, angina chest pain and heart failure.

2. Calcium channel blockers (CCB) are other medications used to lower high blood pressure that can also lower the mood. Nifedipine, verapamil and diltiazem are some of the more commonly used CCB.

3. Statins are used to lower high cholesterol levels but they can also depress the mood. Examples of such statins include atorvastatin, lovastatin and simvastatin. 

4. Diazepam, lorazepan and flurazepam belong to a group of drugs known as benzodiazepines which are used to treat anxiety and insomnia and known to cause depression.

5. Barbiturates like phenobarbitone and secobarbital, which are used to prevent epilepsy and treat anxiety, can also increase a person’s predisposition for developing depression.

6. Analgesics like codeine, morphine and oxycontin are known to leave a person feeling dejected after taking away their pain.

7. Anticonvulsants like ethosuximide and methsuximide which are used to treat seizure disorders, can also cause depression.  

8. Antibiotics, and especially the flouroquinolones like ciprofloxacin and ofloxacin which are used to treat infections of the urinary tract, can also increase a person’s risk of developing depression.

9. Acyclovir, an antiviral used to manage herpes or shingles, is another prescription medication that can cause melancholy.

10. Isotretinoin is a potent vitamin A derivative which is used to treat severe acne and sadly also causes medication induced depression.

Other Causes of Depression

If you are taking any of these medications and you begin feeling blue, do not stop taking them without consulting your doctor because depression has many other causes.

For starters, genetics have a role to play in the development of depression since it has been known to run in some families. Major life events like getting divorced or getting a baby, losing a job, starting a new one and even retiring can all cause depression.

Ongoing traumatic experiences like physical or sexual abuse and even those which happened in a person’s past can all darken their present with depression. These depressing effects of abuse are compounded by social isolation and substance abuse which can also cause depression by their own.

Therefore if you start feeling sad while taking drugs prescribed by your doctor, do not stop taking them. Consult your healthcare provider, tell them your symptoms, voice your suspicions and ask them what you should do.